Melanotan II 10MG (Cyclic α-MSH Analog)
Melanotan II is a synthetic cyclic lactam analog of alpha-melanocyte stimulating hormone (α-MSH) widely used in the literature as a non-selective melanocortin receptor agonist reference compound. For Melanotan II (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2), each vial is labeled 10MG, molecular formula C50H69N15O9, molecular weight 1,024.18 Da, CAS 121062-08-6.
Published laboratory work with Melanotan II (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2) has examined non-selective melanocortin agonist reference studies, melanogenesis and eumelanin synthesis, receptor structure-activity relationship work. Each lot is manufactured under sterile conditions, lyophilized in single-use research vials, and labeled with its production lot for traceability.
Supplied for in-vitro laboratory research use only. Not for human or veterinary consumption, administration, diagnostic or therapeutic use.
Synthetic cyclic α-MSH analog investigated as a non-selective melanocortin receptor agonist in melanogenesis, receptor selectivity and structure-activity research models. Lyophilized under sterile conditions. For laboratory research use only, not for human or veterinary use.
Background reading on this compound in the ENOS Lab Notes: Melanocortin MC4R Ligand Research: What's New in 2026.
Background reading: how to read a certificate of analysis, why purity and identity are separate tests and storage and handling guidance.
Comparing receptor selectivity? See Melanotan I 10MG, the MC1R selective linear analog.
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These products are sold strictly for in-vitro laboratory research and are not intended for human consumption, diagnosis, treatment, or any therapeutic use. Purchaser must be 18 years of age or older and confirms they are a qualified researcher.
Compound identity
Listed on the storefront as Melanotan II. The compound information for this research vial is below.
- Compound name
- Melanotan II (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2)
- Also known as
- MT-II, MT-2, MT2, Melanotan 2, Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
- Molecular formula
- C50H69N15O9
- Molecular weight
- 1,024.18 Da
- CAS number
- 121062-08-6
- Vial size
- 10MG
Product Information
Research DatasheetProduct Overview
Melanotan II is a synthetic cyclic lactam analog of alpha-melanocyte stimulating hormone (α-MSH) widely used in the literature as a non-selective melanocortin receptor agonist reference compound. Laboratory research applications include receptor binding panels, melanogenesis pathway studies in cultured cells, and structure-activity work comparing cyclic and linear α-MSH analogs. Lyophilized under sterile conditions. For laboratory research use only. Not for human or veterinary use.
Molecular Profile
Research Applications
- ◆Non-selective melanocortin agonist reference studies
- ◆Melanogenesis and eumelanin synthesis research
- ◆Receptor structure-activity relationship work
- ◆Comparative α-MSH analog pharmacology
Quality Standards
Lab documentation: available on request, info@enosusa.com
For in-vitro research use only. Not for human consumption, diagnosis, or treatment.
Synthetic cyclic α-MSH analog investigated as a non-selective melanocortin receptor agonist in melanogenesis, receptor selectivity and structure-activity research models. Lyophilized under sterile conditions. For laboratory research use only, not for human or veterinary use. All ENOS research vials are lyophilized, sealed under sterile conditions, and shipped with cold-chain packaging where appropriate.
- ◆Melanocortin receptor research
- ◆Receptor selectivity studies
- ◆10MG lyophilized vial
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